The CHIT1 antibody from MyBioSource.com is a Mouse Monoclonal antibody to CHIT1, chitinase 1, and Chitotriosidase. This antibody recognizes Human antigen. The CHIT1 antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Mouse monoclonal CHIT1 antibody
CHIT1 is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens